Astros starter Framber Valdez made one mistake in seven innings, and it ended up handing him a tough-luck loss as he was outdueled by the Padres' Dylan Cease.

Dylan Cease pitched brilliantly into the ninth inning and Manny Machado, Fernando Tatis Jr. and Donovan Solano hit consecutive homers in the eighth for the San Diego Padres, who beat the AL West-leading Houston Astros 4-0.

Jose Altuve was ejected after disputing an umpire's call and removing his sock to show a supposed foul off his foot during an Astros game.