The low-boil conflict between Israel and Iran has shaped the Middle East for decades. Of the many conflicts that have roiled the region, theirs has long been among the most explosive. The two have attacked each other — mostly quietly and in Iran’s case often by proxy — while avoiding an escalation into direct war.

Blinken will discuss the importance of ending the war in Gaza, ways to chart a post-conflict plan for the Palestinian enclave, and how to reach a diplomatic solution to the conflict between Israel and Hezbollah.