Androgens can drive prostate cancer growth, thus providing the rationale for using deprivation of androgens as a first line of treatment for prostate cancer. Unfortunately, prostate cancer cells adapt ...

The androgen receptor is the primary driver of the initiation and growth of prostate cancer, the second-leading cause of death in men. Looking to have a better understanding of how the androgen ...

A summary of the existing avengers in the treatment of metastatic castration-resistant prostate cancer is provided. The goal is to provide a framework to optimize sequencing of existing avengers to ...

Prostate cancer hijacks the normal prostate's growth regulation program to release the brakes and grow freely, according to Weill Cornell Medicine researchers. The discovery, published Dec. 13 in ...

Researchers from the University of Otago—Ōtākou Whakaihu Waka have created a world-first epigenetic tool that has implications for medicine, sports, and agriculture. In a study published in the ...

Experience with de-intensification of intensified treatment in metastatic castration-sensitive prostate cancer in Venezuela: A pilot study. Factors Associated with Intensification Beyond ADT (Odds ...

A poorly characterized protein, historically thought to be a chaperone or enzyme, may actually be a key player in prostate cancer. In a systematic CRISPR screen, scientists from Arc Institute, UCSF, ...

The evolution of a validated clinical syndrome from an initial recognition of a cluster of symptoms to the clear delineation of a defining set of biochemical, biobehavioral, and physical findings is a ...

The PROTAC market is experiencing rapid growth, driven by rising interest in targeted protein degradation as a next-generation therapeutic approach. Expanding oncology pipelines with drugs in clinical ...

The androgen clock is rewriting the science of aging, offering a precise way to measure hormone exposure and its profound effects on health, longevity, and biology. Study: The androgen clock is an ...