It's a loaded Saturday in college football, full of clashes between ranked teams with playoff implications. Our experts pick every Top 25 matchup.

Meanwhile, in the Big Ten, No. 1 Oregon is hosting No. 20 Illinois, and the Ducks are 21.5-point favorites, according to sports betting apps. Those contrasting lines and the fact we're about halfway through conference play made this week a good time to look at just how much parity exists in each league.

The Orange have excelled on the road, picking up wins at UNLV and N.C. State. Ohio State transfer Kyle McCord, who ranks second in the nation with 360 passing yards per game, should light up the Panthers’ 95th-ranked pass defense. Pitt’s four wins against Power Four teams have come by an average of just over four points per game.