A graphic representation of a round, lumpy, blue protein and a single, comblike, purple strand of RNA interacting with a twisted, double, blue strand of DNA that separates where it meets the RNA. A ...
At the heart of this technology is the Cas9 protein, often likened to molecular scissors, capable of cutting strands of DNA at specific locations dictated by a single guide RNA. With this mechanism, ...
When scientists discovered how bacteria protect themselves against viral invaders, called phages, in the early 2000s, little did they know they’d stumbled upon a revolutionary tool researchers could ...
Illustration of the CRISPR-Cas9 complex, one of the gene-editing tools developed by the Innovative Genomics Institute. The new Center for Pediatric CRISPR Cures will use CRISPR technology to develop ...
A lipid nanoparticle containing mRNA for Cas9 protein and a single guide RNA targeting TTR was infused with the goal of insertion into hepatocytes and blocking of transthyretin production in patients ...