Modeling the economic impact of a CIZ1B biomarker blood test for lung cancer screening in high-risk populations. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract ...

Cancer cells reprogramme their metabolism to support rapid proliferation, survival under stress and adaptation to fluctuating nutrient supplies. Central to this reprogramming is a shift towards ...

Colorectal cancer (CRC) progression critically depends on the tumor microenvironment. PLOD2, an enzyme involved in collagen biosynthesis, is highly expressed in many cancers. While it promotes CRC ...

Glioblastoma is one of the most common and aggressive brain tumors within adult cancer patients. The cancer cells develop ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Investigators led by Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how the metabolism of mitochondria supports ...

A research team has successfully identified a novel DNA damage repair pathway in human cells. This study is the first to discover that proteins present in the nuclear membrane of cells directly ...

BPC-157 and TB-500, originating from gastric and thymic sources respectively, both influence angiogenesis, cytoskeletal ...

In a groundbreaking development, scientists have uncovered a type of immortal cell in laboratory settings, offering unprecedented potential for medical research and treatment. These cells, with their ...

Sjögren’s disease (SjD) is a chronic, multisystem autoimmune disorder characterised by lymphocytic infiltration of exocrine ...