The cyclic GMP-AMP synthase (cGAS)–stimulator of interferon genes (STING) axis constitutes a central pathway in the detection of cytosolic DNA and the initiation of innate immune programmes. Upon ...
The initiation of the innate immune responses relies on the detection of microbes by multiple pattern recognition receptors. Among these receptors, cyclic GMP-AMP synthase (cGAS) has been identified ...
When a cell receives a message from outside, it generates a molecule called cyclic AMP (cAMP) to relay this message. To ensure the signal reaches the correct effector without triggering pathways ...
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