DNA methylation profiles in whole blood samples from 77 patients with CN-AML in The Cancer Genome Atlas (LAML cohort) were analyzed. Individual 5’-cytosine-phosphate-guanine-3’ (CpG) sites were ...
Polβ-dependent DNA demethylation is essential for neuronal development. During neuronal development, DNA demethylation at enhancer regions is required to activate gene expression. In the absence of ...
A new study by scientists at deCODE Genetics, a subsidiary of Amgen, shows that sequence variants drive the correlation between DNA methylation and gene expression. The same variants are linked to ...
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Study reveals DNA methylation score that better detects alcohol intake than standard biomarkers
By Tarun Sai Lomte Scientists identify a DNA methylation alcohol biomarker that tracks exposure and aging signals, offering ...
Chronic diseases such as cardiovascular disease, cancer, and diabetes are driven by systemic inflammation, a natural biological response to harmful stimuli, injuries, or infections. C-reactive protein ...
*Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or ...
Development of a comprehensive cfDNA methylation signature for prognostic, predictive, and diagnostic applications in pancreatic ductal adenocarcinoma (PDA). This is an ASCO Meeting Abstract from the ...
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