Millions of people across the world suffer from Alzheimer’s disease, where sufferers experience memory impairment.
As humans and other animals experience new things, their brains continuously update their memory of past events. These ...
A longstanding question in neuroscience is how mammalian brains (including ours) adapt to external environments, information, and experiences. In a paradigm-shifting study published in Nature, ...
Researchers have discovered the mechanistic steps underlying a new type of synaptic plasticity called behavioral timescale synaptic plasticity (BTSP). The study reveals how the entorhinal cortex (EC) ...
This study illustrates the spatiotemporal dynamics of neuron subtype changes within the entorhinal cortex–hippocampal circuit during Alzheimer’s disease progression. EC-stellate neurons progressively ...
The spread of tau pathology from the entorhinal cortex into the neighboring hippocampus region of the brain is thought to herald the onset of clinical symptoms in AD, but exactly what path does tau ...
The human brain continues to be built after we are born for far longer than previously recognized, suggests research by Shawn Sorrells, assistant professor of neuroscience in the Kenneth P. Dietrich ...
Just as gravity explains how two distant objects can sway each other’s movement in space, synaptic connections may explain how amyloid plaques coax distant tau tangles to spread in the brain. This is ...
A longstanding question in neuroscience is how mammalian brains (including ours) adapt to external environments, information, and experiences. In a paradigm-shifting study published in Nature, ...