Genome-wide association studies (GWAS) have uncovered thousands of risk variants that individually have small effects on the risk of human diseases, including chronic kidney disease, type 2 diabetes, ...
Polygenic risk scores (PRSs)—which summarize the genetic predisposition of an individual to human complex traits or common diseases across the genome—hold promise to advance precision medicine by ...
New methods of analysis and novel markers are currently being identified to predict conditions with polygenic inheritance. These include polygenic risk scores (PRS), which are based on the presence of ...
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