A high-yield, one-pot, scalable reaction facilitates the production of biologically relevant amide compounds using less reactive nitrogen-containing heterocyclic compounds and carboxylic acid without ...
Heterocyclic compounds, defined by ring systems incorporating one or more heteroatoms such as nitrogen, oxygen or sulfur, constitute the backbone of modern drug discovery. Their diverse ring ...
Tautomerism in heterocyclic systems—the reversible migration of protons accompanied by changes in bonding and electronic structure—constitutes a fundamental aspect of chemical behaviour that ...