γδ T cells play a crucial role in immune surveillance and serve as a bridge between innate and adaptive immunity. However, the metabolic requirements and regulation of γδ T-cell development and ...

T lymphocytes expressing γδ T-cell receptors (TCRs) display innate-like effector functions that are preprogrammed during their development in the thymus. This maturation process is regulated by the ...

During prenatal development, the fetus resides in a relatively low-glucose environment compared to the mother, yet must maintain high anabolic activity to support rapid growth. Here, we discover that ...