The updated schema, called MPATH-Dx Version 2.0, simplifies the diagnoses of all melanocytic skin lesions undergoing biopsy into four classes (ranging from MPATH-Dx Class I benign low risk lesions, ...

Melanocytes describe a specialized type of cell that generates a substance called melanin, a pigment responsible for skin and eye color. When several melanocytes cluster together, they form a benign, ...

The first description of a particular melanocytic nevus found in relatives from six cases of melanoma was made in 1978. [1] Although initially coined B-K moles, these moles soon acquired the name ...

RAS proteins are critical for cell divisions, differentiation, and apoptotic processes. Oncogenic RAS variations cause cancer, but they can also induce benign lesions such as thyroid nodules, colonic ...

With the growing number of skin biopsies performed annually for suspected melanoma, a simple, easily understood standardized classification system for melanocytic lesions is increasingly important to ...

BRAF testing timelines and impact on the starting of systemic treatment. This is an ASCO Meeting Abstract from the 2021 ASCO Annual Meeting I. This abstract does not include a full text component.

Please provide your email address to receive an email when new articles are posted on . Brain and/or spinal MRI were effective in detecting melanin in the central nervous system of children with ...

Generally larger with irregular borders, dysplastic nevi are acquired melanocytic skin lesions. What is the best location to sample when obtaining a punch biopsy from a potential dysplastic nevus or ...

(CMN) result from the benign proliferation of melanocytic cells during intrauterine life. Historic information about the identification of CMN is limited. In the late nineteenth and early twentieth ...

A randomized phase II study of sunitinib versus dacarbazine in the treatment of patients with metastatic uveal melanoma. BREAK-MB: A phase II study assessing overall intracranial response rate (OIRR) ...