All life on earth depends upon the process of mitosis or cell division in which the chromosomal content of a cell is equally divided between two new cells. For mitosis to occur, the chromosomes in ...

How cell division occurs and is coordinated with organismal development is subject of intense research interest, as is how this process malfunctions in the development of tumors. Researchers have been ...

Centrosomes consist of two centrioles surrounded by an amorphous pericentriolar matrix (PCM), but it is unknown how centrioles and PCM are connected. We show that the centrioles in Drosophila embryos ...

Centrioles are surrounded by pericentriolar material (PCM), which is proposed to promote new centriole assembly by concentrating γ-tubulin. Here, we quantitatively monitor new centriole assembly in ...

The centrosome is the main microtubule-organizing centre in animal cells and has many crucial functions, including the assembly of the mitotic spindle and establishing the axis of cell division. It ...

Newly formed centrioles can spring forth from clouds of pericentriolar material, violating the precise regulation of centriole counting. These observations challenge the long-standing view that ...

Mitosis is the process by which the genetic information encoded on chromosomes is equally distributed to two daughter cells, a fundamental feature of all life on earth. Scientists led by Alexander ...

EPFL scientists discover that certain cell structures, the centrioles, could act as information carriers throughout cell generations. The discovery raises the possibility that transmission of ...

The new information, plus new tools for centriole manipulation, should help researchers figure out how p53 helps safeguard cells, and how it causes cancers when it doesn't. "P53 was already known to ...

This news release is available in German. The duplication of cellular contents and their distribution to two daughter cells during cell division are amongst the most fundamental features of all life ...