In A Nutshell Your brain amplifies cold signals during fever. When you’re sick, a molecule called prostaglandin E2 cranks up ...

Skeletal muscles harbor quiescent muscle-specific stem cells (MuSCs) capable of tissue regeneration throughout life. Muscle injury precipitates a complex inflammatory response in which a multiplicity ...

Prostaglandin E 2 (PGE 2), a bioactive lipid derived from arachidonic acid, mediates a broad range of physiological processes through four G protein-coupled receptor (GPCR) subtypes: EP1–EP4. While ...

Prostaglandin E2(PGE2), a major product of cyclooxygenase, has been implicated in modulating angiogenesis, vascular function, and inflammatory processes, but the underlying mechanism is not clearly ...

In the relaxation of the smooth muscle, PGE1 works mainly via the prostaglandin E2 receptor (EP receptors). After combining to EP receptor, PGE1 acts by increasing the synthesis of cyclic-adenosine ...

Prostaglandins induce the regeneration of muscle in rodents and humans through the prostaglandin E2 receptor EP4 subtype receptor, but this therapeutic pathway's potential is limited due to systemic ...

Aging populations in developed countries are facing an increasing challenge, as frailty and disability emerge as significant health concerns. Sarcopenia – the age-related loss of muscle mass and ...

As we age, it gets harder to recover from a fall, injury or even a tough workout because the body’s muscle-repair system starts to falter. Muscle stem cells (MuSCs), the in-house repair crew, stop ...

This is a preview. Log in through your library . Abstract The antidiuretic hormone arginine vasopressin is a systemic effector in urinary concentration. However, increasing evidence suggests that ...

Prostaglandins are natural chemicals in the body with hormone-like qualities. First discovered in semen, prostaglandins were later found in cells throughout the body, as well as in women’s menstrual ...

Researchers at Stanford University School of Medicine and Sanford Burnham Prebys have discovered that targeting an enzyme associated with aging after nerve injury in a mouse model with a small ...