A computational biology company that started in space tech is looking to change how biopharma finds disease targets by modeling how proteins behave.

Proteins are the molecular machines of cells. They are produced in protein factories called ribosomes based on their blueprint—the genetic information. Here, the basic building blocks of proteins, ...

Protein folding is a critical process by which linear chains of amino acids adopt specific three‐dimensional conformations essential for biological function. In recent years, studies have increasingly ...

AI pioneer Vishal Sikka warns to never trust an LLM that runs alone interview Don't trust; verify. According to AI researcher ...

Just as a misshapen key can't open a lock, the proteins in our cells need to have the correct 3D shape to function properly. And defects in a protein's structure can cause diseases. Proteins are ...

An illustration of antibodies, colored pink and blue, over a white background. Antibodies’ flexible loop structures make them difficult to crack with artificial intelligence. Credit: Ian C.

Origami is collaborating with Ipsen to develop molecules designed to remove or correct abnormal proteins in neurodegenerative diseases.

In order to fulfil their many functions, proteins must be folded into the correct shape. Researchers at the University of Basel have now discovered tiny “folding factories” in cells that enable ...

I read with interest your report on protein folding.1 You cited C. Levinthal, Journal of Chemical Physics, 65:44-5, 1968 to illustrate the difficulty in the folding problem: "[Levinthal's paradox] ...

Protein folding helpers such as TRiC and prefoldin (PFD) are crucial for the correct folding of many essential proteins. In a Nature study, researchers from the Max Planck Institute of Biochemistry ...