Scientists have uncovered a surprising dual identity of stellate cells—star-shaped liver cells once known only for causing liver scarring. Before they turn destructive, these cells act as crucial ...

The field of liver research has benefited enormously from technological breakthroughs. We now have access to single-cell ...

Study suggests that persistently activated ATF6α is a tumor driver, a potential stratification marker for immunotherapy response, and a therapeutic target for HCC.

This new review article highlights the critical role of ribosome biogenesis in liver health and disease progression. As the center of protein synthesis, ribosomes influence liver regeneration, ...

Many people who die from sepsis die of organ failure, including liver failure, which is a common, often fatal complication. For many years, the underlying causes and mechanisms of sepsis-induced liver ...

Scientists have found that combining silybin with carvedilol works far better against liver fibrosis than either drug alone. The duo targets the root drivers of liver scarring, sharply reducing ...

Transcription Factors (TFs) are pivotal regulators of gene expression and have been implicated in a variety of diseases, including cancer, neurological disorders, autoimmune conditions, and metabolic ...