San Francisco 49ers wide receiver Deebo Samuel takes a reverse flea-flicker screen pass for a 21-yard gain.

The San Francisco 49ers entered Sunday's matchup at Lambeau Field against the Green Bay Packers with a depleted roster. On ...

Emotions ran high before the San Francisco 49ers and Green Bay Packers faced off in their Week 12 matchup at Lambeau Field.

The 49ers will play without left tackle Trent Williams in their starting lineup for the first time this season, putting ...

San Francisco 49ers left tackle Trent Williams has been sidelined for the team's Week 12 matchup vs. the Green ...

The 49ers are in a world of hurt, both literally and figuratively.A report earlier Sunday indicated the 49ers were optimistic ...

San Francisco 49ers quarterback Brock Purdy underwent an MRI early last week after sustaining a shoulder injury in the team's ...

The San Francisco 49ers have released the list of inactive players for their Week 12 matchup against the Green Bay Packers.

Before the 49ers play the Packers on Sunday at Lambeau Field, tune into "49ers Pregame Live" at noon PT on NBC Sports Bay ...

The San Francisco 49ers find themselves at 5-5 in the NFC West standings during a disappointing 2024 campaign. Facing a ...

San Francisco 49ers head coach Kyle Shanahan announced that the team has ruled out quarterback Brock Purdy for Sunday's ...

NFL Network's Kurt Warner and Steve Mariucci on why the San Francisco 49ers are struggling in red zone.