The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in ...

The 49ers have revealed their latest injury report from Wednesday’s practice before their Sunday Night Football tilt against ...

San Francisco 49ers head coach Kyle Shanahan told reporters that star quarterback Brock Purdy will practice with the team ...

The Bills and 49ers meet on Sunday Night Football in a game with playoff implications for both teams. Here are three ...

San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there ...

San Francisco 49ers quarterback and Iowa State alum Brock Purdy is showing promising signs after being injured on Nov. 17.

San Francisco 49ers quarterback Brock Purdy missed last week's game against the Green Bay Packers. Will he play against the ...

The San Francisco 49ers' 2024 season has not gone as planned. Sitting at 5-6 and in last place in the NFC West, the team is ...

The 49ers got blown out by the Packers in Week 12 and rookie wideout Ricky Pearsall was held without a catch for the second ...

LB Fred Warner, WR Deebo Samuel Sr., RB Christian McCaffrey and DL Nick Bosa identified key areas for improvement as the team ...

There's no denying that it's trending towards a lost season for the San Francisco 49ers. What was once a season with so much ...

Sunday, 8:20 p.m. EST, NBC BetMGM NFL odds: Bills by 7. Series record: Bills lead 7-6. Against the spread: 49ers 4-7, Bills 7 ...