The Buffalo Bills might have a chance to clinch the AFC East on Sunday night when they battle the injury-decimated San ...

Brock Purdy missed the 49ers' last game against the Packers, but the Bills are preparing as if he's playing on Sunday night.

The 49ers are welcoming Brock Purdy back to practice today after shoulder soreness kept him out of Sunday’s loss at Green Bay.

SANTA CLARA — While Brock Purdy resumed practicing through a shoulder issue and Dre Greenlaw made a much-anticipated debut ...

All six of the NFL teams playing on Thanksgiving will be without critical players. The Chicago Bears will be without center ...

There were a couple of huge upsets in Week 12 of the NFL season and Sports Illustrated's Conor Orr nailed one of them, ...

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in ...

The banged-up San Francisco 49ers received some positive news on Wednesday. Per ESPN's Nick Wagoner, 49ers head coach Kyle ...

LB Fred Warner, WR Deebo Samuel Sr., RB Christian McCaffrey and DL Nick Bosa identified key areas for improvement as the team ...

The 49ers have revealed their latest injury report from Wednesday’s practice before their Sunday Night Football tilt against ...

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an ...

There's no denying that it's trending towards a lost season for the San Francisco 49ers. What was once a season with so much ...