The Bills are 9-2, their best start since 1992, and with a win would clinch their fifth straight AFC East title.

Purdy is officially listed as questionable for the game, though coach Kyle Shanahan said the plan is for him to start on ...

When Brock Purdy started looking visibly uncomfortable during the fourth quarter of his Week 11 showdown against the Seattle ...

San Francisco's starting quarterback missed last week's loss to the Packers. Here's the latest on whether he'll play in primetime on Sunday.

San Francisco 49ers head coach Kyle Shanahan spoke with reporters via a conference call on Monday, providing several injury updates following the team's 38-10 loss to the Green Bay Packers. ...

The results were ugly for the San Francisco 49ers last week against the Green Bay Packers without starting quarterback Brock ...

It’s not like he was throwing at game speed, but the sight of Brock Purdy throwing the ball during warmups Friday was ...

Brock Purdy revealed what he thought about while standing on the sideline at the of the San Francisco 49ers' loss to the ...

San Francisco 49ers quarterback Brock Purdy is poised to return to action on Sunday night against the Buffalo Bills after ...

There are no teams on bye around the NFL in Week 13, which means we'll be treated to a packed slate of Sunday games even ...

Left tackle Trent Williams (ankle) and rusher Nick Bosa (hip/oblique), who also did not play in Week 12, were also absent ...

Check out the top 10 catches from San Francisco 49ers tight end George Kittle from his eight year career, so far.