The San Francisco 49ers will be missing two of their best players in their must-win matchup against the Green Bay Packers ...

The San Francisco 49ers fell to 5-6 on the season in losing to the Green Bay Packers on Sunday. Top takeaways with Brock ...

Big news and not good news out of the Bay Area on Friday. The 5-5 San Francisco 49ers will be in Green Bay on Sunday to play ...

The San Francisco 49ers will be without their starting quarterback and their best defensive player when they visit the Green ...

Brandon Allen will start in place of an injured Brock Purdy when the 49ers (5-5) also have to play without Nick Bosa on ...

Jaire Alexander, Edgerrin Cooper, Brock Purdy and Nick Bosa were all ruled out Friday; 49ers LT Trent Williams joins them on ...

The Seattle Seahawks' arch rivals, the San Francisco 49ers, did not just lose a game last week. Their 20-17 defeat proved to ...

The 49ers have ruled out quarterback Brock Purdy for Sunday’s game against the Packers. It appeared to be trending that way ...

San Francisco 49ers quarterback Brock Purdy will not play Sunday and head coach Kyle Shanahan said the lingering discomfort ...

San Francisco 49ers quarterback Brock Purdy will miss Sunday's game against the Green Bay Packers with a sore throwing ...

This just isn't the 49ers' week. They have now been dealt the worst-case scenario with Nick Bosa's status against the Packers ...

San Francisco 49ers defensive end Nick Bosa missed Wednesday's practice as the team began preparations for Sunday's game ...