The Boston Red Sox open up a crucial series against the San Diego Padres on Friday, with both teams surging toward first ...

A shooting shut down streets in downtown San Diego Friday evening. The shooting happened along 1st Avenue near Horton Plaza and the Westin.

A teenage resident who had recently traveled overseas has been confirmed as the first measles case in San Diego County this year.

It's an emotional day for many people in San Diego who don't have a place to call home. For one woman, the word "homeless" is hopefully a thing of the past.

One of the best sci-fi shows of the past decade has left our orbit in a series finale that was as full of heart, hope, and ...