From the front, Arkansas Fried Chicken looks mostly unharmed, but the EF3 tornado that ripped through the neighborhood Friday ...

Dr. Brett Waite lost 35 pounds — not with a trendy app or drugs, but with the guidance of a local weight loss coach, Charles ...

Tuesday's announcement is a major shift in the FDA’s approach to updating vaccines that protect against COVID-19.

Some former weather service veterans worry that overworked meteorologists and violent weather are a dangerous combination.

Other companies, domestic and foreign, have recently warned customers that price hikes related to tariffs are on the way.

MASCOUTAH, Ill — Our weekly Travel Tip is brought to you by MidAmerica St. Louis Airport — where travel is easy, affordable, ...

A recall of the popular rolling coolers has expanded to more than 1.1 million units after dozens of reports of finger ...

Angela Nelson fears history may be repeating itself as St. Louis struggles to recover from the May 16 tornado.

WASHINGTON — President Donald Trump is heading to Capitol Hill early Tuesday to seal the deal on his “big, beautiful bill," ...

The New Orleans Saints quarterback competition heats up with Spencer Rattler vying for a fair shot against Tyler Shough.

Fans can now listen to the re-recorded version of Taylor Swift's hit song "Look What You Made Me Do (Taylor's Version)" from her "Reputation" album.

ST. LOUIS — Not even one year after the newly built Delmar Maker District was established, many businesses face destruction on Delmar Boulevard. Last July, 5 On Your Side featured multiple new ...