Former Buffalo Bills defensive end Leonard Floyd spoke about facing his old team on Sunday night with the San Francisco 49ers ...

The Buffalo Bills might have a chance to clinch the AFC East on Sunday night when they battle the injury-decimated San ...

See who's in and who's out for the Week 13 matchup between the Buffalo Bills and San Francisco 49ers on December 1, 2024.

All six of the NFL teams playing on Thanksgiving will be without critical players. The Chicago Bears will be without center ...

Bad news for the 49ers. Brock Purdy still isn't ready to resume throwing. Technically, he threw one pass on Wednesday -- a ...

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in ...

The banged-up San Francisco 49ers received some positive news on Wednesday. Per ESPN's Nick Wagoner, 49ers head coach Kyle ...

The 49ers have revealed their latest injury report from Wednesday’s practice before their Sunday Night Football tilt against ...

San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there ...

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an ...

Watch the best plays from Week 12 of the 2024 NFL season. NFL Network's Kyle Brandt and Peter Schrager review the best play ...

There's no denying that it's trending towards a lost season for the San Francisco 49ers. What was once a season with so much ...