The running back position took a massive hit in Week 13 for the San Francisco 49ers. Christian McCaffrey (knee) and Jordan Mason (ankle) sustained injuries in t ...

Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

Christian McCaffrey on Wednesday shared his first message to his fans after suffering a season-ending injury on Sunday.

Having suffered a knee injury that landed him on injured reserve during a snowy loss to the Bills on Sunday night, 49ers ...

Running back Christian McCaffrey is on injured reserve for the second time this season, but San Francisco 49ers coach Kyle ...

Christian McCaffrey's injury-ridden season took another unfortunate turn when the star running back went down with another ...

McCaffrey immediately checked himself out of the game and ran right into the medical tent. The 49ers star RB missed the ...

San Francisco 49ers running back Christian McCaffrey scared NFL fans across the country this Wednesday with a heartfelt ...

Isaac Guerendo didn’t start in college until his final game.. He starts at running back for the 49ers Sunday against Chicago.

McCaffrey appeared to have finally gotten untracked against ... and Guerendo became the lead runner for a team that is sixth ...

Christian McCaffrey suffered a torn PCL in the San Francisco 49ers' 35-10 Week 13 loss to the Buffalo Bills. The injury is ...

On Wednesday, McCaffrey, the former Carolina Panthers star, shared his initial thoughts on the 2024 NFL season following his ...