San Francisco 49ers quarterback Brock Purdy feels sorry for the brutal injury suffered by Christian McCaffrey.

It's Buffalo Bills vs San Francisco 49ers in Week 13 of the NFL season. Can Josh Allen and company outduel Christian McCaffery and Deebo Samuel?

This has led to a profound resource drain to the 49ers. They kept up their turn-and-burn roster approach of letting guys ...

The 49ers were absolutely shellacked Sunday for a second straight week as the Buffalo Bills beat them 35-10 on national ...

Temperatures reached the 20s Sunday night as snow fell throughout Buffalo’s Week 13 home game against San Francisco. For the ...

Injuries and missed opportunities have defined the San Francisco 49ers' 2024 season. Can they overcome setbacks and make a ...

Sunday after the 49ers lost their seventh game, I asked Brock Purdy to make of the terrible season the 49ers are having. Here ...

The San Francisco 49ers are in dire straights after a blowout loss to the Buffalo Bills, and QB Brock Purdy knows it.

The situation for the San Francisco 49ers is so dire that Brock Purdy had to send a clear and forceful message to his ...

Kirk Cousins threw four interceptions and tossed the Atlanta Falcons’ playoff plans into disarray. Brock Purdy couldn’t ...

Back-to-back blowout losses and another injury to star back Christian McCaffrey might just be the final blow to the dwindling ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...