Purdy is officially listed as questionable for the game, though coach Kyle Shanahan said the plan is for him to start on ...

This week, Nick Bosa was asked about the 49ers' upcoming opponent, Bills quarterback Josh Allen. Here's what Bosa said. Q: ...

San Francisco 49ers defensive end Nick Bosa (97) celebrates after sacking Tampa Bay Buccaneers quarterback Baker Mayfield ...

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

Defensively, two of the 49ers’ best players this season are out and will not travel as defensive end Nick Bosa (obliques, ...

The San Francisco 49ers fell to 5-6 on the season in losing to the Green Bay Packers on Sunday. Top takeaways with Brock ...

Jaire Alexander, Edgerrin Cooper, Brock Purdy and Nick Bosa were all ruled out Friday; 49ers LT Trent Williams joins them on ...

Bosa (hip/oblique) has been ruled out for Sunday's game against Buffalo, Lindsey Pallares of the 49ers ' official site reports.

The 49ers are taking stock of their injury situation but could be getting some key players back for Buffalo game.

Neil Reynolds, Jeff Reinebold and Phoebe Schecter discuss San Franciscos playoff prospects on the Inside The Huddle Pofcast; ...

First comes Brock Purdy, the team's star quarterback, who missed Week 12 with a right shoulder. While Purdy is still ...

The San Francisco 49ers are up against the Buffalo Bills in Week 13. The 49ers have dealt with an array of injuries this ...