18 antibiotics RESISTANCE in 2 year old .. A. β-Lactamase Production (सबसे common) Bacteria β-lactam ring को तोड़ देते हैं → drug inactive Types (step-wise evolution): Narrow spectrum β-lactamase Penicillinase (early Staph) ESBL (Extended Spectrum β-Lactamase) CTX-M, TEM, SHV Resistance to 3rd gen cephalosporins Common in E. coli, Klebsiella India में community-acquired भी common AmpC β-lactamase Cephamycins 3rd gen ceph resistant Inducible (Enterobacter, Citrobacter) Carbapenemases (Biggest thr
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