Male vs. Female brains - what is the difference? Largest functional brain imaging study to date identifies specific brain differences between women and men, according to a report in the Journal of Alzheimer’s Disease. In the largest functional brain imaging study to date, the Amen Clinics compared 46,034 brain SPECT imaging studies provided by 11 clinics, quantifying differences between the brains of men and women. The study is published in the Journal of Alzheimer’s Disease. The brains of women