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Pyrexia is any temperature over 38.2 (100.7F) but there are two types of pyrexia. Intrinsic is induced by your immune system - typically white blood cells called Macrophages that produce pyrogens (heat stimulating chemicals ) instructing your brains thermostat to raise. These intrinsic pyrexia are simply called FEVER and are most commonly triggered by infection. Extrinsic Pyrexia is called Hyperthermia and triggered by an outside influence like heat, or certain medications (Serotonergic, Dopamin
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Antipyretic drugs are medications used to reduce fever (pyrexia). Fever is a common symptom of infections such as viral fever, bacterial infections, malaria, and inflammatory conditions. These drugs help bring down elevated body temperature and provide symptomatic relief. How Do Antipyretic Drugs Work? Fever occurs when pyrogens increase prostaglandin E2 (PGE2) production in the hypothalamus, raising the body’s temperature set point. Antipyretics work by: ✔️ Inhibiting cyclooxygenase (COX) enzym
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