OPTIMA aims to find out if using a test called Prosigna, can help make safe and accurate decisions about whether or not chemotherapy treatment is needed for patients with ER-positive, HER2-negative early breast cancer. "We know that we often are giving chemotherapy to women who don't get a benefit from it, so OPTIMA is trying to see if a test on someone's breast cancer tumour can work out whether they might be able to do just as well without having to receive chemotherapy." - OPTIMA Study Chair,
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